Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling
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چکیده
منابع مشابه
Notoginsenoside R7 suppresses cervical cancer via PI3K/PTEN/Akt/mTOR signaling
Notoginsenoside R7 was isolated from Panax notoginseng, a plant used commonly in traditional Chinese medicine. We investigated the anti-cancer effects of R7 in HeLa cells in vitro and in vivo, and explored the underlying mechanisms of action. R7 dose-dependently inhibited HeLa cell proliferation and induced apoptosis in vitro, In silico docking-based screening assays showed that R7 can directly...
متن کاملCervical cancer
سرویکس یا گردن رحم قسمتی از اندام تولید زنانه است که دهانه آن به داخل واژن باز می شود. بعضی اعمال آن عبارتند از : تولید مواد نرم کننده واژن - تولید موکوس که کمک به حرکت اسپرم می کند- حفظ جنین در رحم در طول بارداری
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.22721